Question

Help! Help me plz!

2. What is the function of GAA?

A.) *GAA breaks enzymes down into small pieces the cell can use*
B.) GAA speeds up the creation of glycogen from glucose subunits
C.) GAA speeds up the breakdown of glycogen into glucose subunits

4. What causes tissue to break down in people with Pompe disease?

A.) A build up of broken enzymes blocks blood flow in capillaries, eventually resulting in death.
B.) *Enlarged lysosomes weaken tissue and burst lysosomes damage tissue with acid.*
C.) High blood sugar causes diabetic shock.

6. One codon codes for...

A.) *one amino acid*
B.) one protein
C.) one nucleotide
D.) one gene


7. A change to DNA is called a _____________.

*There are no options for this question but I believe the answer is mutation*


8. For an individual to develop Pompe disease, they must have two alleles for the broken GAA enzyme.

A.) True
B.) *False*

Answer 1

2. The answer is; C

GAA gene code for the acid alpha-glucosidase enzyme occasionally referred to as acid maltase. The enzyme is found in lysosomes where it is used to break down glycogen to glucose by attacking the glycosidic bonds.

4. The answer is; B

People with Pompe disease have a deficiency in the production of the acid alpha-glucosidase enzyme. This, therefore, leads to the accumulation of glycogen in the lysosomes because they are not being broken down. The lysosomes, therefore, enlarge and eventually burst to spill their degradative content in the cell. These enzymes begin breaking down the cells and tissues.

6. The answer is; A

One codon is composed of 3 nucleotides base sequence. These bases are sent on an mRNA that is used by the ribosome to translate proteins. Each codon codes for an amino acid which is brought in by tRNAs and a peptide bond is formed with an adjacent amino acid ( coded for by the adjacent codon in the mRNA).

7. The answer is; mutation

Mutation alters the original sequence of nucleotide bases on the DNA. This is caused by mutagens. The mutation could be beneficial or deleterious to the organism when the mutated DNA codes for a different functional or structural protein, or have no effect at all (when the mutated DNA codes for the same protein)

8. The answer is; A

Pompe disease is an autosomal recessive disorder meaning you have to have both of the two alleles as recessive. Having one dominant allele of the GAA gene will mask the effect of the recessive allele and the person will not exhibit the disease.