Question

How does binding of complement-opsonized microbes to CR1 facilitate clearing of the microbe from the host? a. Secretion of proinflammatory cytokines b. All of the answers occur as a result of CR1 binding of complement-opsonized microbes. c. Promotion of phagocytosis of opsonized microbes by leukocytes d. None of the answers occur. e. Mediating phagocytosis of C3b-opsonized pathogen by B cells

Answer 1

The correct answer is - b. All of the answers occur as a result of CR1 binding of complement-opsonized microbes.

Step-by-step explanation:

Binding of complement - opsonized to CR1 makes the microbe palatable to the phagocyte for the phagocytosis and removes the microbe from the host cell. The mechanism of the removal takes place by the promotion of phagocytosis by the leukocytes.

Secretion of the pro-inflammatory cytokines also takes place in the clearing of the microbe and the phagocytosis is mediated by the B cells of the C3b-opsonized pathogen.