Answer:
The U.S. Food and Drug Administration warns that taking higher than recommended doses of Benadryl can lead to serious heart problems, seizures, coma, or even death. Oral Benadryl products shouldn’t be taken more than 6 times each day. For adults and children over 12 years of age, the maximum is 300 mg each day. For children ages 6 to 12 years, the maximum is 150 mg each day. For adults or children, Benadryl products such as the cream, gel, and spray shouldn’t be applied to the skin more than 4 times per day.